U12 minor spliceosomal RNA

U12 minor spliceosomal RNA
Predicted secondary structure and sequence conservation of U12
Identifiers
SymbolU12
RfamRF00007
Other data
RNA typeGene; snRNA; splicing
Domain(s)Eukaryota
GOGO:0000371 GO:0045131 GO:0005693
SOSO:0000399
PDB structuresPDBe

U12 minor spliceosomal RNA is formed from U12 small nuclear (snRNA), together with U4atac/U6atac, U5, and U11 snRNAs and associated proteins, forms a spliceosome that cleaves a divergent class of low-abundance pre-mRNA introns. Although the U12 sequence is very divergent from that of U2, the two are functionally analogous.

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