2,2,2-Trichloroethanol

2,2,2-Trichloroethanol
Names
	Preferred IUPAC name 2,2,2-Trichloroethan-1-ol
Identifiers
CAS Number	115-20-8 ;
3D model (JSmol)	Interactive image;
Beilstein Reference	1697495
ChEBI	CHEBI:28094 ;
ChEMBL	ChEMBL1171 ;
ChemSpider	7961 ;
ECHA InfoCard	100.003.701
EC Number	204-071-0;
Gmelin Reference	2407
IUPHAR/BPS	2293;
KEGG	C07490 ;
PubChem CID	8259;
UNII	AW835AJ62N ;
CompTox Dashboard (EPA)	DTXSID1021950 ;
	InChI InChI=1S/C2H3Cl3O/c3-2(4,5)1-6/h6H,1H2 Key: KPWDGTGXUYRARH-UHFFFAOYSA-N ; InChI=1/C2H3Cl3O/c3-2(4,5)1-6/h6H,1H2 Key: KPWDGTGXUYRARH-UHFFFAOYAW;
	SMILES ClC(Cl)(Cl)CO;
Properties
Chemical formula	C2H3Cl3O
Molar mass	149.40 g/mol
Density	1.55 g/cm3
Melting point	17.8 °C (64.0 °F; 290.9 K)
Boiling point	151 °C (304 °F; 424 K)
Hazards
	GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H302, H315, H318, H336
Precautionary statements	P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P362, P403+P233, P405, P501
Flash point	88 °C (190 °F; 361 K)
Safety data sheet (SDS)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

2,2,2-Trichloroethanol is the chemical compound with formula Cl₃C−CH₂OH. Its molecule can be described as that of ethanol, with the three hydrogen atoms at position 2 (the methyl group) replaced by chlorine atoms. It is a clear flammable liquid at room temperature, colorless when pure but often with a light yellow color.

The pharmacological effects of this compound in humans are similar to those of its prodrug chloral hydrate, and of chlorobutanol. Historically, it has been used as a sedative hypnotic. The hypnotic drug triclofos (2,2,2-trichloroethyl phosphate) is metabolized in vivo to 2,2,2-trichloroethanol. Chronic exposure may result in kidney and liver damage.

2,2,2-Trichloroethanol can be added to SDS-PAGE gels in order to enable fluorescent detection of proteins without a staining step, for immunoblotting or other analysis methods.