Thioflavin

Thioflavin T
Names
	Preferred IUPAC name 2-[4-(Dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium chloride
Identifiers
CAS Number	2390-54-7 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:88013 ;
ChEMBL	ChEMBL224392 ; ChEMBL224392 ;
ChemSpider	16062 ;
ECHA InfoCard	100.017.482
PubChem CID	16953;
UNII	CAX9SG0II0 ;
CompTox Dashboard (EPA)	DTXSID10883841 ;
	InChI InChI=1S/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1 Key: JADVWWSKYZXRGX-UHFFFAOYSA-M ; InChI=1/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1 Key: JADVWWSKYZXRGX-REWHXWOFAC;
	SMILES [Cl-].s2c1cc(ccc1[n+](c2c3ccc(N(C)C)cc3)C)C;
Properties
Chemical formula	C17H19ClN2S
Molar mass	318.86 g/mol
Density	1.301 g/cm3
Melting point	137.9 °C (decomp.)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Thioflavins are fluorescent dyes that are available as at least two compounds, namely Thioflavin T and Thioflavin S. Both are used for histology staining and biophysical studies of protein aggregation. In particular, these dyes have been used since 1989 to investigate amyloid formation. They are also used in biophysical studies of the electrophysiology of bacteria. Thioflavins are corrosive, irritant, and acutely toxic, causing serious eye damage. Thioflavin T has been used in research into Alzheimer's disease and other neurodegenerative diseases.