List of tallest buildings in Panama City

This list of tallest buildings in Panama City ranks skyscrapers in Panama City, by height. The tallest completed building in Panama City is The Ocean Club Tower - P.H. TOC JW Marriott Panama, which stands 284.4 m (933 ft) tall.

For several years, Panama City's skyline remained largely unchanged, with only four buildings exceeding 150 m (492 feet). Beginning in the early 2000s, the city experienced a large construction boom, with new buildings rising up all over the city and two new tallest buildings since 2005. Several supertall buildings were also planned for construction; as of September 2007 all of these have been either cancelled (Palacio de la Bahía, and Torre Generali) or are on hold (Faros de Panamá, Torre Central).

Various reasons, including the annual transit of fourteen thousand ships through the country, the one hundred and fifty international banks that have their headquarters in the city and that house corporate capital, have motivated the so-called real estate boom, an effect that has resulted in the construction of high-rise buildings, of more than fifty floors. As of 2024, Panama City has over 68 skyscrapers over 150 meters (492 feet) tall, the most out of any city in Latin America.

Panama City began with the construction of the Cathedral of Our Lady of the Assumption, standing 27 meters tall and one of the tallest in the city in the 17th century. Beginning with the end of the 20th century, the city has become one of the capitals with the most skyscrapers on the North American continent. In the early 2000s, the city experienced a major construction boom, with new buildings growing up all over the city.