Lymphotoxin beta receptor

LTBR
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1RF3, 4MXW
Identifiers
Aliases	LTBR, CD18, D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFR3, TNFRSF3, lymphotoxin beta receptor
External IDs	OMIM: 600979; MGI: 104875; HomoloGene: 1753; GeneCards: LTBR; OMA:LTBR - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	6,391,571 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	125,290,848 bp
RNA expression pattern
	Top expressed in
	right lobe of thyroid gland; ; left lobe of thyroid gland; ; minor salivary glands; ; body of pancreas; ; body of stomach; ; upper lobe of left lung; ; muscle layer of sigmoid colon; ; right lobe of liver; ; left uterine tube; ; skin of abdomen;
	Top expressed in
	granulocyte; ; duodenum; ; gastric mucosa; ; epithelium of stomach; ; yolk sac; ; mucous cell of stomach; ; right kidney; ; saccule; ; membranous bone; ; left lobe of liver;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; tumor necrosis factor-activated receptor activity; identical protein binding; ubiquitin protein ligase binding;
Cellular component	integral component of membrane; membrane; plasma membrane; integral component of plasma membrane; Golgi apparatus;
Biological process	myeloid dendritic cell differentiation; tumor necrosis factor-mediated signaling pathway; positive regulation of JNK cascade; multicellular organism development; cellular response to mechanical stimulus; response to lipopolysaccharide; regulation of cell population proliferation; positive regulation of extrinsic apoptotic signaling pathway; inflammatory response; viral process; signal transduction; apoptotic process; immune response; positive regulation of I-kappaB kinase/NF-kappaB signaling; hematopoietic or lymphoid organ development;
	Sources:Amigo / QuickGO
Orthologs
	4055
	17000
	ENSG00000111321
	ENSMUSG00000030339
	P36941
	P50284
	NM_001270987; NM_002342
	NM_010736
	NP_001257916; NP_002333
	NP_034866
	Wikidata
View/Edit Human	View/Edit Mouse

Lymphotoxin beta receptor (LTBR), also known as tumor necrosis factor receptor superfamily member 3 (TNFRSF3), is a cell surface receptor for lymphotoxin involved in apoptosis and cytokine release. It is a member of the tumor necrosis factor receptor superfamily.