Imagabalin

Imagabalin
Clinical data
Other namesPD-0332334; PD-332,334
ATC code
  • None
Identifiers
  • (3S,5R)-3-amino-5-methyloctanoic acid
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC9H19NO2
Molar mass173.256 g·mol−1
3D model (JSmol)
  • O=C(O)C[C@@H](N)C[C@@H](CCC)C
  • InChI=1S/C9H19NO2/c1-3-4-7(2)5-8(10)6-9(11)12/h7-8H,3-6,10H2,1-2H3,(H,11,12)/t7-,8+/m1/s1
  • Key:JXEHXYFSIOYTAH-SFYZADRCSA-N

Imagabalin (INN, USAN; PD-0332334) was an investigational drug that acts as a ligand for the α2δ subunit of the voltage-dependent calcium channel, with some selectivity for the α2δ1 subunit over α2δ2. It was under development by Pfizer as a pharmaceutical medication due to its hypothesized anxiolytic, analgesic, hypnotic, and anticonvulsant-like activity. It reached phase-III clinical trials for treatment of generalized anxiety disorder; however, the trials were terminated by the manufacturer. The drug is no longer under development.

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