HYAL1

HYAL1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2PE4
Identifiers
Aliases	HYAL1, HYAL-1, LUCA1, NAT6, MPS9, hyaluronoglucosaminidase 1, hyaluronidase 1
External IDs	OMIM: 607071; MGI: 96298; HomoloGene: 5277; GeneCards: HYAL1; OMA:HYAL1 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	50,312,381 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	107,458,909 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; spleen; ; apex of heart; ; left ventricle; ; human kidney; ; right lung; ; upper lobe of left lung; ; right adrenal gland; ; right adrenal cortex; ; left adrenal gland;
	Top expressed in
	hepatobiliary system; ; liver; ; proximal tubule; ; urinary bladder; ; white adipose tissue; ; genital tubercle; ; esophagus; ; lip; ; lung; ; zone of skin;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transcription factor binding; hydrolase activity, acting on glycosyl bonds; catalytic activity; hydrolase activity; hyaluronan synthase activity; hyalurononglucosaminidase activity;
Cellular component	cytoplasm; hyaluranon cable; extracellular region; lysosomal lumen; lysosome; extracellular exosome; cytoplasmic vesicle; extracellular space;
Biological process	hyaluronan biosynthetic process; hyaluronan catabolic process; positive regulation of hyaluranon cable assembly; positive regulation of epithelial cell proliferation; response to reactive oxygen species; response to antibiotic; cellular response to tumor necrosis factor; positive regulation of epithelial cell migration; cellular response to platelet-derived growth factor stimulus; positive regulation of growth; cellular response to fibroblast growth factor stimulus; positive regulation of angiogenesis; cellular response to pH; cartilage development; positive regulation of cell growth; cellular response to UV-B; negative regulation of cell growth; cellular response to interleukin-1; chondroitin sulfate catabolic process; embryonic skeletal joint morphogenesis; metabolism; inflammatory response; positive regulation of cell adhesion; hyaluronan metabolic process; positive regulation of G1/S transition of mitotic cell cycle; carbohydrate metabolic process; response to virus; viral entry into host cell;
	Sources:Amigo / QuickGO
Orthologs
	3373
	15586
	ENSG00000114378
	ENSMUSG00000010051
	Q12794
	Q91ZJ9
NM_033159; NM_153281; NM_153282; NM_153283; NM_153284;
	NM_153285; NM_153286
	NM_008317; NM_001331161
	NP_149349; NP_695013; NP_695014; NP_695015; NP_695017
	NP_001318090; NP_032343
	Wikidata
View/Edit Human	View/Edit Mouse

Hyaluronidase-1 is an enzyme that in humans is encoded by the HYAL1 gene.