Denileukin diftitox

Denileukin diftitox
Clinical data
Trade namesOntak, others
AHFS/Drugs.comMonograph
MedlinePlusa611024
License data
Routes of
administration
Intravenous
Drug classAntineoplastic
ATC code
Legal status
Legal status
Pharmacokinetic data
Elimination half-life70-80 min
Identifiers
  • Diphtheria toxin-Interleukin-2 fusion protein
CAS Number
IUPHAR/BPS
DrugBank
ChemSpider
  • none
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC2560H4042N678O799S17
Molar mass57647.46 g·mol−1
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Denileukin diftitox, sold under the brand name Ontak among others, is an anti-cancer medication used for the treatment of adults with T-cell lymphoma. It is an IL2-receptor-directed cytotoxin. It is an engineered protein combining interleukin-2 and diphtheria toxin.